The so called, blood-brain barrier! “The drug will not work for you Mrs. Robinson; it cannot cross the blood brain barrier.” It turns out that what we always think must always be true, is not necessarily so. This recent study on the USE OF ULTRASOUND in drug treatment may be relevant to many patients, especially those with neurologic or organic brain disease.
“Nearly two decades ago, scientists discovered that those microbubbles (harmlessly injected with the use of clinical ultrasound) could do something else: They could shake loose the blood-brain barrier. This impassable membrane is why neurological conditions like epilepsy, Alzheimer’s, and Parkinson’s are so hard to treat: 98 percent of drugs simply can’t get to the brain. If you station a battalion of microbubbles at the barrier and hit them with a focused beam of ultrasound, the tiny orbs begin to oscillate and grow. Then, like some Grey Wizard magic, the blood-brain barrier opens—and for a few hours, any drugs in the bloodstream can slip in. Things like chemo drugs, or anti-seizure medications.”
The Technical Director of Vital Health Scores has used microbubbles or blood contrast agents many times, mainly to help identify abnormal communications between the heart chambers or help see the pumping function of the heart. Ultrasonic contrast agents are used to perfuse tissue in the major organs of the abdomen to help characterize benign versus malignant lesions in the liver, kidney, and pancreas. ASK your provider! The article continues:
“More recently, scientists have realized that the blood-brain barrier isn’t the only tissue that could benefit from ultrasound and microbubbles. The colon, for instance, is pretty terrible at absorbing the most common drugs for treating Crohn’s disease, ulcerative colitis, and other inflammatory bowel diseases. So they’re often delivered via enemas—which, inconveniently, need to be left in for hours.”